MR tissue phase mapping reveals reduced left ventricular velocities in patients with myocardial scar

Background Cardiac magnetic resonance (CMR) imaging is the reference standard for assessing biventricular systolic function. However, global measures of systolic function (i.e. ejection fraction) are relatively insensitive to regional alterations in myocardial structure, creating a need for quantitative analysis for regional myocardial function. Tissue phase mapping (TPM) is a CMR imaging technique that measures the regional myocardial velocities with high temporal resolution, complete left ventricular (LV) coverage, and full access to the 3-directional myocardial velocities. In this study, we evaluated the impact of myocardial scar detected with delayed enhancement imaging (DE-CMR) in patients with suspected infiltrative cardiomyopathy on global and regional myocardial velocities and dyssynchrony measured by TPM, comparing the results with controls.